Microbiota: Impact across the lifespan, from childhood to old age

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Imagine a simple dietary change that improves your health from infancy to old age. Bifidobacteria, beneficial gut microorganisms, are key to this transformation. Dominant in breastfed babies, they break down specific carbohydrates into beneficial compounds, improving gut health and overall metabolism. By supporting the growth of bifidobacteria, you can improve immunity, bone health, weight management, and even mood.

Promoting lifelong health through bifidobacteria

Bifidobacteria, integral members of the gut microbial community, influence various aspects of health, especially in breastfed infants, where they dominate. These beneficial microorganisms possess a unique carbohydrate metabolic pathway, breaking down specific carbohydrates into short-chain fatty acids (SCFAs) and lactate. The breakdown products and metabolites positively influence the gut environment and extend their reach into host metabolism through the gut-brain axis, offering fertile ground for continued exploration, with research opportunities and benefits spanning all life stages.

Lifelong benefits of bifidobacteria

Supporting the growth of bifidobacteria produces a multitude of health benefits tailored to different life stages. In childhood, one of their benefits is that they can help control allergies. During childhood and adolescence, bifidobacteria contribute to improved calcium absorption and growth. They also positively affect cognition, potentially supporting the learning process. In adulthood, they support blood sugar control and aid in healthy weight management, promoting greater satiety and contributing to positive changes in inflammatory processes. Later in adulthood, they support bone mineral density for stronger bones, strengthen the immune system, and play a role in the management of autoimmune diseases. Emerging science is delving deeper into their potential impact on mood, including anxiety and depression. These are just a few highlights to show how bifidobacteria are versatile health allies at various life stages.

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Importance in early life: Bifidobacteria in newborns

The establishment of the intestinal microbiota in newborns is a critical phase, with bifidobacteria taking center stage in breastfed babies. Human milk oligosaccharides (HMOs) act as the first "prebiotics" for these babies, supporting the growth of bifidobacteria. In babies fed formulas without enriched prebiotics, the microbiota composition is different. Recognizing the gold standard established by breastfed babies, promoting the growth of bifidobacteria becomes imperative for long-term health benefits.

Prebiotic fibers: a tailor-made boost for bifidobacteria

Prebiotics emerge as powerful tools for selectively supporting the growth of bifidobacteria. The distinct ß-2,1 linkages of fibers such as inulin and oligofructose, for example, and the specialized enzyme system of bifidobacteria create an environment in which these microorganisms thrive, providing a competitive advantage in the intricate intestinal ecosystem. A recent systematic review and meta-analysis published by Nagy et al. (2022) demonstrated established evidence on the impact of these chicory root prebiotics on the abundance of bifidobacteria in the intestine, confirming that intake of at least 3 g per day of chicory root fiber significantly increases bifidobacteria selectively in the general population, with significant improvements in intestinal function.

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Bifidobacteria and host support: An established alliance

Scientific consensus confirms that bifidobacteria actively contribute to host health through metabolic, structural, and protective functions. These microorganisms play key roles in inhibiting the growth of potential pathogens, stimulating immune responses, restoring the gut microbiota during antibiotic therapy, producing essential vitamins, and influencing various aspects of the intestinal ecosystem.

Microbiota dysbiosis: a buzzword

Currently, the term "dysbiosis" is in vogue worldwide, becoming widely recognized and discussed. Expanding knowledge about the relationships between microbiota and disease reveals correlations between dysbiosis and various diseases. Low numbers of bifidobacteria are observed in conditions such as type 2 diabetes mellitus, inflammatory bowel diseases, celiac disease, obesity/metabolic disorders, and Helicobacter pylori infections. Treating dysbiosis by increasing bifidobacteria intake, facilitated by proven prebiotic fibers, is emerging as a preventative measure that supports overall health.

Bifidogenic attributes of prebiotic fibers

The properties of bifidobacteria are closely aligned with the bifidogenic attributes of prebiotics, specifically chicory root fiber. This alignment highlights the potential health benefits supported by chicory root fiber, including improving the gut environment, enhancing intestinal barrier function and gut function, supporting the immune system, bone mineralization, weight management, blood glucose regulation, mood and cognition, autoimmune diseases, and mitigating systemic inflammation.

Untying the Knots: Bifidobacteria, Prebiotics, and Well-Being

As we explore the web of health connections between bifidobacteria and prebiotics, particularly prebiotic fibers, the potential for preventative and therapeutic interventions becomes increasingly clear. This alliance paves the way for healthier, more resilient lives across all age groups. Don't miss additional insights as we delve deeper into the intricate world of gut health and its profound impact on the health and wellness markets. In the next issue, we'll explore the wonders of digestive health and wellness. Stay tuned!

 

References
BENEO Institute. (2023). Bifidobacteria in their natural gut ecosystem: How bifidobacteria support health. Fact sheet. 5 pages.
BENEO Institute. (2023). The uniqueness of inulin and oligofructose from the chicory root: Why their scientific uniqueness translates into an improved diet for the consumer. Fact sheet. 6 pages.
Gibson and Roberfroid, (1995) J.Nutr. 125: 1401-1412;
Gibson et al (2017): Nature reviews. Gastroenterology & hepatology 14 (8), S. 491–502.
Nagy et al. (2022) Crit Rev Food Sci Nutr:1–18. https://www.tandfonline.com/doi/pdf/10.1080/10408398.2022.2098246?needAccess=true
Rastall RA (2023) Chinese Journal of Nutrition, Vol 45, No 2, 2023
Reimer R. (2023); Today's Dietitian Spring Symposium, Savannah, US, May 2023
Vijay and Valdes (2022): European journal of clinical nutrition 76 (4), S. 489–501.
Article written by Renata Càssar, Nutrition Communications Manager for Latin America at BENEO (a leading producer and supplier of plant-based ingredients with health and nutritional benefits). Renata is a subject matter expert with a degree in nutrition, a master's degree, and an MBA. In her current role at BENEO and the BENEO Institute, Renata interacts with customers and healthcare professionals, sharing knowledge that underpins BENEO's ingredients.

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